Translation examples
Ei ole muunnos neurosteroidin allopregnanoloni (5AR tyyppi I) ja DHT (5AR tyyppi II), joten väär
There is no conversion from neurosteroid allopregnanolone (5AR type I) to DHT(5AR type II), so false claims of using Procepia (Finasteride) which inhibits 5AR type II or Dutasteride which inhibits both 5AR type I and type II would be completely ineffective.
5α-reduktaasit katalysoivat tiettävästi ainakin seuraavia reaktioita: Kolestenoni → 5α-Kolestanoni Progesteroni → 5α-Dihydroprogesteroni 3α-Dihydroprogesteroni → Allopregnanoloni 3β-Dihydroprogesteroni → Isopregnanoloni Deoksikortikosteroni → 5α-Dihydrodeoksikortikosteroni Kortikosteroni → 5α-Dihydrokortikosteroni Kortisoli → 5α-Dihydrokortisoli Aldosteroni → 5α-Dihydroaldosteroni Androsteenidioni → 5α-Androsteenidioni Testosteroni → 5α-Dihydrotestosteroni 5α-reduktaasin salpaajia kuten finasteridiä ja dutasteridiä käytetään lääkkeinä miestyypin kaljuuntumiseen.
The following reactions are known to be catalyzed by 5α-reductase: Cholestenone → 5α-Cholestanone Progesterone → 5α-Dihydroprogesterone 3α-Dihydroprogesterone → Allopregnanolone 3β-Dihydroprogesterone → Isopregnanolone Deoxycorticosterone → 5α-Dihydrodeoxycorticosterone Corticosterone → 5α-Dihydrocorticosterone Cortisol → 5α-Dihydrocortisol Aldosterone → 5α-Dihydroaldosterone Androstenedione → 5α-Androstanedione Testosterone → 5α-Dihydrotestosterone The mechanism of 5α reductase inhibition is complex, but involves the binding of NADPH to the enzyme followed by the substrate.
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