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Daily PCA administration in diet over the lifespan of rats (2 years)was associated with increased incidences of adrenal medulla hyperplasia (increased cell growth) in female rats, and increased incidences of pigmentation in the renal tubule epithelium, olfactory epithelium, and hepatocytes of male and female rats.
La administración diaria de PCA en la ingesta durante toda la vida de las ratas (2 años) se asoció a una mayor incidencia de hiperplasia medular suprarrenal (mayor crecimiento celular) en ratas hembra, y a una mayor incidencia de la pigmentación del epitelio del túbulo renal, el epitelio olfativo y los hepatocitos de ratas macho y hembra.
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