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At 2.5 and 5.0 mg/kg bw/d liver weight was increased pentobarbital sleeping time was decreased and induction of aminopyrine demethylaseaniline hydroxylase was found as well as a dose-related increase in amino-transferase activity and spontaneous lipid peroxidation.
При дозах в 2,5 и 5,0 мг/кг м.т./сут наблюдались увеличение массы печени, сокращение продолжительности сна под воздействием пентобарбитала и индукция аминопирин деметилазеанилин гидроксилазы, а также - в зависимости от дозы - повышенная активация аминотрансферазы и самопроизвольная пероксидация липидов.
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