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Formation of this metabolite is mediated by cytochrome P450 3A monooxygenases, which are expressed only in male rats (Birner et al., 1995; Werner et al., 1995a).
La formation de ce métabolite est catalysée par les monooxygénases cytochrome P450 3A, qui se trouvent uniquement chez les rats mâles (Birner et al., 1995; Werner et al., 1995a).
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