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La formación de este metabolito se realiza mediante monooxigenasas 3A del citocromo P450, que se expresan únicamente en ratas macho (Birner et al., 1995; Werner et al., 1995a).
Formation of this metabolite is mediated by cytochrome P450 3A monooxygenases, which are expressed only in male rats (Birner et al., 1995; Werner et al., 1995a).
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