Esempi di traduzione.
This metabolite has been found to be cytotoxic to proximal tubular cells in vitro without activation by ß-lyase (Birner et al., 1995).
Se ha observado que este metabolito es citotóxico in vitro para las células de los túbulos proximales sin activación por beta-liasa (Birner et al., 1995).
An additional β - lyase independent metabolic activation reaction resulting in the formation of vinylsulfoxide has been described by Birner et al. (1997) and was detected more pronounced in male rats.
Birner et al. (1997) han descrito una reacción adicional de activación metabólica independiente de beta - liasa, resultante en la formación de vinil sulfóxido y detectada de manera más pronunciada en ratas macho.
Contributing to the weight of evidence are observations of mutagenicity in bacteria under conditions that favor the GSH/mercapturate/-lyase pathway, genotoxicity in mammalian cells, and in vivo DNA binding in rats and mice.
Contribuyen al peso de la evidencia las observaciones de mutagenia en bacterias en condiciones que favorecen la ruta del GSH/mercapturato/beta-liasa, la genotoxicidad en células de mamífero y la unión al ADN in vivo en ratas y ratones.
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